Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction

Abstract We previously identified two isoforms of T-type, voltage-gated calcium (Cav3) channels (Cav3.1, Cav3.2) that are functionally expressed in murine lymphatic muscle cells; however, contractile tests of lymphatic vessels from single and double Ca v 3 knock-out (DKO) mice, exhibited nearly iden...

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Bibliographic Details
Main Authors: Michael J. Davis, Jorge A. Castorena-Gonzalez, Scott D. Zawieja
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42877-6