Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

Abstract Background Frailty is a major age‐associated syndrome leading to disability. Oxidative damage plays a significant role in the promotion of frailty. The cellular antioxidant system relies on reduced nicotinamide adenine dinucleotide phosphate (NADPH) that is highly dependent on glucose 6‐P d...

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Bibliographic Details
Main Authors: Coralie Arc‐Chagnaud, Andrea Salvador‐Pascual, Esther Garcia‐Dominguez, Gloria Olaso‐Gonzalez, Angela G. Correas, Eva Serna, Thomas Brioche, Angele Chopard, Pablo J. Fernandez‐Marcos, Manuel Serrano, Antonio L. Serrano, Pura Muñoz‐Cánoves, Vicente Sebastiá, Jose Viña, Mari Carmen Gomez‐Cabrera
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Aging
Antioxidant
Mitochondria
Disability
Healthspan
NADPH
Online Access:https://doi.org/10.1002/jcsm.12792

Internet

https://doi.org/10.1002/jcsm.12792

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