Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system

Summary: Hydrogen sulfide (H2S) is a gaseous microbial metabolite whose role in gut diseases is debated, with contradictory results stemming from experimental difficulties associated with accurate dosing and measuring H2S and the use of model systems that do not accurately represent the human gut en...

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Bibliographic Details
Main Authors: Justin A. Hayes, Anna W. Lunger, Aayushi S. Sharma, Matthew T. Fernez, Rebecca L. Carrier, Abigail N. Koppes, Ryan Koppes, Benjamin M. Woolston
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014936