Giant Depolarizing Potentials Trigger Transient Changes in the Intracellular Cl- Concentration in CA3 Pyramidal Neurons of the Immature Mouse Hippocampus

Giant Depolarizing Potentials Trigger Transient Changes in the Intracellular Cl- Concentration in CA3 Pyramidal Neurons of the Immature Mouse Hippocampus

Giant depolarizing potentials (GDPs) represent a typical spontaneous activity pattern in the immature hippocampus. GDPs are mediated by GABAergic and glutamatergic synaptic inputs and their initiation requires an excitatory GABAergic action, which is typical for immature neurons due to their elevate...

Full description

Bibliographic Details
Main Authors: Aniello Lombardi, Peter Jedlicka, Heiko J. Luhmann, Werner Kilb
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
development
Cl- homeostasis
gramicidin-perforated patch-clamp
post-synaptic currents
ionic plasticity
GABA(A) receptors
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00420/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00420/full

Similar Items