A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages

<p>Abstract</p> <p>Background</p> <p>Macrophages and dendritic cells (DCs) play key roles in host defense against HSV-1 infection. Although macrophages and DCs can be infected by herpes simplex virus type 1 (HSV-1), both cell types are resistant to HSV-1 replication. Th...

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Bibliographic Details
Main Authors: Town Terrence, Wechsler Steven L, UnderHill David, Mott Kevin R, Ghiasi Homayon
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/56