Activity of protease-activated receptors in primary cultured human myenteric neurons

Activity of the four known protease-activated receptors (PARs) has been well studied in rodent enteric nervous system and results in animal models established an important role for neuronal PAR2. We recently demonstrated that, unlike in rodents, PAR1 is the dominant neuronal protease receptor in the...

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Bibliographic Details
Main Authors: Eva Maria Kugler, Gemma eMazzuoli, Ihsan Ekin Demir, Gueralp Onur Ceyhan, Florian eZeller, Michael eSchemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00133/full