Detection of MDM2 gene amplification on tissue microarray-based Fluorescence In-Situ Hybridization (FISH) in well-differentiated and dedifferentiated liposarcomas, displaying a wide morphological spectrum: A validation study at a tertiary cancer referral centre

Detection of MDM2 gene amplification on tissue microarray-based Fluorescence In-Situ Hybridization (FISH) in well-differentiated and dedifferentiated liposarcomas, displaying a wide morphological spectrum: A validation study at a tertiary cancer referral centre

Background: Liposarcomas including atypical lipomatous tumors (ALT)/well-differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas (DDLPSs) display a histomorphological spectrum with their several diagnostic mimics. Murine double minute 2(MDM2) gene amplification characterizes ALT/WDLPS...

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Bibliographic Details
Main Authors: Bharat Rekhi, Nupur Karnik, Radhika Agrawal, Omshree Shetty, Shraddha Patkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
dedifferentiated liposarcoma
fish
liposarcoma
mdm2
tissue microarray
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=1;spage=65;epage=75;aulast=Rekhi

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http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=1;spage=65;epage=75;aulast=Rekhi

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