Decoding pooled RNAi screens by means of barcode tiling arrays
<p>Abstract</p> <p>Background</p> <p>RNAi screens via pooled short hairpin RNAs (shRNAs) have recently become a powerful tool for the identification of essential genes in mammalian cells. In the past years, several pooled large-scale shRNA screens have identified a vari...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
|
Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/11/7 |