Decoding pooled RNAi screens by means of barcode tiling arrays

<p>Abstract</p> <p>Background</p> <p>RNAi screens via pooled short hairpin RNAs (shRNAs) have recently become a powerful tool for the identification of essential genes in mammalian cells. In the past years, several pooled large-scale shRNA screens have identified a vari...

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Bibliographic Details
Main Authors: Dotan Iris, Hachmo Yafit, Gholami Amin, Fredebohm Johannes, Boettcher Michael, Canaani Dan, Hoheisel Jörg D
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/7