β-caryophyllene and docosahexaenoic acid, isolated or associated, have potential antinociceptive and anti-inflammatory effects in vitro and in vivo

Abstract Inflammation is a complex biological response involving the immune, autonomic, vascular, and somatosensory systems that occurs through the synthesis of inflammatory mediators and pain induction by the activation of nociceptors. Staphylococcus aureus, the main cause of bacteremia, is one of...

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Main Authors: Laís Ferraz Brito Sousa, Hellen Braga Martins Oliveira, Nathan das Neves Selis, Lorena Lobo Brito Morbeck, Talita Costa Santos, Lucas Santana Coelho da Silva, Jully Chayra Santos Viana, Mariane Mares Reis, Beatriz Almeida Sampaio, Guilherme Barreto Campos, Jorge Timenetsky, Regiane Yatsuda, Lucas Miranda Marques
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23842-1