Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock

Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock

Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role of the sclerotome in establishing the axial skeleton is unclear. We severely disrupt zebrafis...

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Bibliographic Details
Main Authors: Laura Lleras Forero, Rachna Narayanan, Leonie FA Huitema, Maaike VanBergen, Alexander Apschner, Josi Peterson-Maduro, Ive Logister, Guillaume Valentin, Luis G Morelli, Andrew C Oates, Stefan Schulte-Merker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
notochord
somitogenesis clock
somite
Entpd5
Online Access:https://elifesciences.org/articles/33843

Internet

https://elifesciences.org/articles/33843

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