Sacubitril/valsartan combination enhanced cardiac glycophagy and prevented the progression of murine diabetic cardiomyopathy

Sacubitril/valsartan combination enhanced cardiac glycophagy and prevented the progression of murine diabetic cardiomyopathy

Background: Diabetic cardiomyopathy (DCM) is linked to disturbance in cardiac glucose handling and increased cardiac glycogen storage. This study tested the potential role of sacubitril/valsartan on the progression of DCM in high fat diet (HFD)/streptozotocin (STZ)-induced type 2 diabetic rats compa...

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Bibliographic Details
Main Authors: Dina Salem Abdelaziz Elshenawy, Nehal Mohammed Ramadan, Vivian Boshra Abdo, Rehab Hamdy Ashour
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diabetes mellitus
Diabetic cardiomyopathy
Glycogen
Glycophagy
Heart failure
Sacubitril/valsartan
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222007715

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http://www.sciencedirect.com/science/article/pii/S0753332222007715

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