Uncovering the molecular and physiological processes of anticancer leads binding human serum albumin: A physical insight into drug efficacy.

Human serum albumin (HSA) has its ability to bind drug molecules and influence their efficacies. Although anticancer leads NSC48693 and NSC290956 functioned at the same mechanism, the drug efficacies were obviously distinct. To gain insight into the distinct drug efficacy, the molecular and physiolo...

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Bibliographic Details
Main Authors: Chuanbo Liu, Zuojia Liu, Jin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5398698?pdf=render