Defects of Nutrient Signaling and Autophagy in Neurodegeneration

Defects of Nutrient Signaling and Autophagy in Neurodegeneration

Neurons are post-mitotic cells that allocate huge amounts of energy to the synthesis of new organelles and molecules, neurotransmission and to the maintenance of redox homeostasis. In neurons, autophagy is not only crucial to ensure organelle renewal but it is also essential to balance nutritional n...

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Bibliographic Details
Main Authors: Jon Ondaro, Haizea Hernandez-Eguiazu, Maddi Garciandia-Arcelus, Raúl Loera-Valencia, Laura Rodriguez-Gómez, Andrés Jiménez-Zúñiga, Julen Goikolea, Patricia Rodriguez-Rodriguez, Javier Ruiz-Martinez, Fermín Moreno, Adolfo Lopez de Munain, Ian James Holt, Francisco Javier Gil-Bea, Gorka Gereñu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neurodegenerative diseases
autophagy
nutrient sensing pathways
mitochondrial metabolism
lipid metabolism
glucose metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.836196/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.836196/full

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