Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway

Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway

Chondrosarcoma is a malignant bone tumor that is characterized by high metastatic potential and marked resistance to radiation and chemotherapy. The knowledge that adipokines facilitate the initiation, progression, metastasis, and treatment resistance of various tumors has driven several in vitro an...

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Bibliographic Details
Main Authors: Shih-Ya Hung, Chih-Yang Lin, Cheng-Chieh Yu, Hsien-Te Chen, Ming-Yu Lien, Yu-Wen Huang, Yi-Chin Fong, Ju-Fang Liu, Shih-Wei Wang, Wei-Cheng Chen, Chih-Hsin Tang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
visfatin
chondrosarcoma
metastasis
matrix metalloproteinase-2
AP-1
Online Access:https://www.mdpi.com/1422-0067/22/16/8642

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https://www.mdpi.com/1422-0067/22/16/8642

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