Direct interaction with 14–3-3γ promotes surface expression of Best1 channel in astrocyte

Direct interaction with 14–3-3γ promotes surface expression of Best1 channel in astrocyte

Abstract Background Bestrophin-1 (Best1) is a calcium-activated anion channel (CAAC) that is expressed broadly in mammalian tissues including the brain. We have previously reported that Best1 is expressed in hippocampal astrocytes at the distal peri-synaptic regions, called microdomains, right next...

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Bibliographic Details
Main Authors: Soo-Jin Oh, Junsung Woo, Young-Sun Lee, Minhee Cho, Eunju Kim, Nam-Chul Cho, Jae-Yong Park, Ae Nim Pae, C. Justin Lee, Eun Mi Hwang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Brain
Subjects:
Astrocyte
Bestrophin-1
14–3-3γ
Surface expression
Glutamate
Online Access:http://link.springer.com/article/10.1186/s13041-017-0331-x

Internet

http://link.springer.com/article/10.1186/s13041-017-0331-x

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