Spontaneous development of neoplasms in severe combined immunodeficient mice
Severe combined immunodeficient (SCID) mice lack functional T and B cells. This renders them useful for implantation of human cells. The absence of immune cells, however, makes severe combined immunodeficient mice highly susceptible to infections and spontaneous development of malignancies; 2 of 114...
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Format: | Article |
Language: | English |
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SAGE Publishing
2015-01-01
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Series: | SAGE Open Medical Case Reports |
Online Access: | https://doi.org/10.1177/2050313X14568698 |