Rare variants in complement system genes associate with endothelial damage after pediatric allogeneic hematopoietic stem cell transplantation

Rare variants in complement system genes associate with endothelial damage after pediatric allogeneic hematopoietic stem cell transplantation

IntroductionComplement system has a postulated role in endothelial problems after hematopoietic stem cell transplantation (HSCT). In this retrospective, singlecenter study we studied genetic complement system variants in patients with documented endotheliopathy. In our previous study among pediatric...

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Bibliographic Details
Main Authors: Lilli Leimi, Jessica R. Koski, Outi Kilpivaara, Kim Vettenranta, A. Inkeri Lokki, Seppo Meri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
hematopoietic stem cell transplantation
hematopoietic stem cell transplantation adverse effects
acute toxicity
vascular complications
complement system
endothelial damage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1249958/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1249958/full

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