The P2X7R-NLRP3 and AIM2 Inflammasome Platforms Mark the Complexity/Severity of Viral or Metabolic Liver Damage

The P2X7R-NLRP3 and AIM2 Inflammasome Platforms Mark the Complexity/Severity of Viral or Metabolic Liver Damage

P2X7R-NLRP3 and AIM2 inflammasomes activate caspase-1 and the release of cytokines involved in viral-related liver disease. Little is known about their role in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steato-hepatitis (NASH). We characterized the role of inflammasomes in NAFLD, NA...

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Bibliographic Details
Main Authors: Chiara Rossi, Antonio Salvati, Mariarosaria Distaso, Daniela Campani, Francesco Raggi, Edoardo Biancalana, Domenico Tricò, Maurizia Rossana Brunetto, Anna Solini
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
P2X7 receptor
NLRP3
AIM2
non-alcoholic fatty liver disease
HCV infection
Online Access:https://www.mdpi.com/1422-0067/23/13/7447

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https://www.mdpi.com/1422-0067/23/13/7447

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