Single cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection

Myeloid cells are increasingly recognized as major players in transplant rejection. Here, we used a murine kidney transplantation model and single cell transcriptomics to dissect the contribution of myeloid cell subsets and their potential signaling pathways to kidney transplant rejection. Using a v...

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Bibliographic Details
Main Authors: Anil Dangi, Naveen R. Natesh, Irma Husain, Zhicheng Ji, Laura Barisoni, Jean Kwun, Xiling Shen, Edward B. Thorp, Xunrong Luo
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-10-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.141321