Differential regulation of adhesion complex turnover by ROCK1 and ROCK2.

ROCK1 and ROCK2 are serine/threonine kinases that function downstream of the small GTP-binding protein RhoA. Rho signalling via ROCK regulates a number of cellular functions including organisation of the actin cytoskeleton, cell adhesion and cell migration.In this study we use RNAi to specifically k...

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Bibliographic Details
Main Authors: Frances E Lock, Katie R Ryan, Natalie S Poulter, Maddy Parsons, Neil A Hotchin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278444?pdf=render