Spadin Modulates Astrocytic Passive Conductance via Inhibition of TWIK-1/TREK-1 Heterodimeric Channels

Astrocytes, the most abundant cell type in the brain, are non-excitable cells and play critical roles in brain function. Mature astrocytes typically exhibit a linear current–voltage relationship termed passive conductance, which is believed to enable astrocytes to maintain potassium homeostasis in t...

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Bibliographic Details
Main Authors: Yeonju Bae, Jae Hyouk Choi, Kanghyun Ryoo, Ajung Kim, Osung Kwon, Hyun-Gug Jung, Eun Mi Hwang, Jae-Yong Park
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/24/9639