Osseointegration of Titanium Implants in a Botox-Induced Muscle Paralysis Rat Model Is Sensitive to Surface Topography and Semaphorin 3A Treatment

Osseointegration of Titanium Implants in a Botox-Induced Muscle Paralysis Rat Model Is Sensitive to Surface Topography and Semaphorin 3A Treatment

Reduced skeletal loading associated with many conditions, such as neuromuscular injuries, can lead to bone fragility and may threaten the success of implant therapy. Our group has developed a botulinum toxin A (botox) injection model to imitate disease-reduced skeletal loading and reported that boto...

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Bibliographic Details
Main Authors: Jingyao Deng, D. Joshua Cohen, Michael B. Berger, Eleanor L. Sabalewski, Michael J. McClure, Barbara D. Boyan, Zvi Schwartz
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomimetics
Subjects:
titanium implants
surface topography
biomimetic multiscale micro/nano texture
osseointegration
botox
semaphorin 3A
Online Access:https://www.mdpi.com/2313-7673/8/1/93

Internet

https://www.mdpi.com/2313-7673/8/1/93

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