Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone

Background: Paget’s disease of bone (PDB) is characterized by focal areas of dysregulated bone turnover resulting in increased bone loss and abnormal bone formation with variable severity. PDB has a complex etiology and both genetics and environmental factors have been implicated. A recent study has...

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Bibliographic Details
Main Authors: Ilhame Diboun, Sachin Wani, Stuart H. Ralston, Omar M. E. Albagha
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.903612/full