Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans

Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans

Condensins are molecular motors that compact DNA via linear translocation. In Caenorhabditis elegans, the X-chromosome harbors a specialized condensin that participates in dosage compensation (DC). Condensin DC is recruited to and spreads from a small number of recruitment elements on the X-chromoso...

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Bibliographic Details
Main Authors: Jun Kim, David S Jimenez, Bhavana Ragipani, Bo Zhang, Lena A Street, Maxwell Kramer, Sarah E Albritton, Lara H Winterkorn, Ana K Morao, Sevinc Ercan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
condensin
Hi-C
3D genome organization
loop extrusion
X-chromosome
TADs
Online Access:https://elifesciences.org/articles/68745

Internet

https://elifesciences.org/articles/68745

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