Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver

Melanocortin 1 receptor (MC1-R) is widely expressed in melanocytes and leukocytes and is thus strongly implicated in the regulation of skin pigmentation and inflammation. MC1-R has also been found in the rat and human liver, but its functional role has remained elusive. We hypothesized that MC1-R is...

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Bibliographic Details
Main Authors: Keshav Thapa, James J Kadiri, Karla Saukkonen, Iida Pennanen, Bishwa Ghimire, Minying Cai, Eriika Savontaus, Petteri Rinne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/84782