Characterization and functional analyses of the human HTR1A gene: 5’ regulatory region modulates gene expression in vitro

Characterization and functional analyses of the human HTR1A gene: 5’ regulatory region modulates gene expression in vitro

Abstract Background The serotonin neurotransmitter (5-HT) and its receptors have important roles in neuropsychiatric disorders such as schizophrenia. The aim of this study was to investigate the functional sequences of the 5′ regulation region of the human HTR1A gene to explore the effects on the ex...

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Bibliographic Details
Main Authors: Xue Wu, Feng-ling Xu, Mei Ding, Jing-jing Zhang, Jun Yao, Bao-jie Wang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genetics
Subjects:
Human HTR1A gene
Promoter
Transcriptional regulation
5-HT1A receptor
Schizophrenia
Online Access:http://link.springer.com/article/10.1186/s12863-018-0708-6

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http://link.springer.com/article/10.1186/s12863-018-0708-6

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