APOBEC3B: Pathological consequences of an innate immune DNA mutator
Cancer is a disease that results from alterations in the cellular genome. Several recent studies have identified mutational signatures that implicate a variety of mutagenic processes in cancer, a major one of which is explained by the enzymatic activity of the DNA cytosine deaminase, APOBEC3B. As a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
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Series: | Biomedical Journal |
Subjects: | |
Online Access: | http://www.biomedj.org/article.asp?issn=2319-4170;year=2015;volume=38;issue=2;spage=102;epage=110;aulast=Burns |