APOBEC3B: Pathological consequences of an innate immune DNA mutator

Cancer is a disease that results from alterations in the cellular genome. Several recent studies have identified mutational signatures that implicate a variety of mutagenic processes in cancer, a major one of which is explained by the enzymatic activity of the DNA cytosine deaminase, APOBEC3B. As a...

Full description

Bibliographic Details
Main Authors: Michael B Burns, Brandon Leonard, Reuben S Harris
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2015;volume=38;issue=2;spage=102;epage=110;aulast=Burns