Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice

Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice

7DW8-5 is a potent glycolipid adjuvant that improves malaria vaccine efficacy in mice by inducing IFN-γ and increasing protective CD8<sup>+</sup> T cell responses. The addition of 7DW8-5 was previously shown to improve the efficacy of a CD8<sup>+</sup> T cell-mediated heterol...

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Bibliographic Details
Main Authors: Felicia N. Watson, Caroline J. Duncombe, Anya C. Kalata, Ethan Conrad, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, Moriya Tsuji, Melanie J. Shears, Sean C. Murphy
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
7DW8-5
adjuvant
sex
<i>Plasmodium</i>
malaria
vaccine
Online Access:https://www.mdpi.com/2218-273X/13/1/8

Internet

https://www.mdpi.com/2218-273X/13/1/8

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