21q22 amplification detection in three patients with acute myeloid leukemia: cytogenomic profiling and literature review

21q22 amplification detection in three patients with acute myeloid leukemia: cytogenomic profiling and literature review

Abstract Background 21q22 amplification is a rare cytogenetic aberration in acute myeloid leukemia (AML). So far, the cytogenomic and molecular features and clinical correlation of 21q22 amplification in AML have not been well-characterized. Case presentation Here, we describe a case series of three...

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Bibliographic Details
Main Authors: Emily M. Kudalkar, Changlee Pang, Mary M. Haag, Daniel A. Pollyea, Manali Kamdar, Gang Xu, Meng Su, Billie Carstens, Karen Swisshelm, Liming Bao
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Molecular Cytogenetics
Subjects:
Acute myeloid leukemia
Chromosome 21q22
Amplification
Cytogenomic
Outcomes
Online Access:https://doi.org/10.1186/s13039-022-00606-0

Internet

https://doi.org/10.1186/s13039-022-00606-0

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