Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases

Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases (CVD). We aim to investigate mechanisms underlying relationships between MDD and CVD in the context of shared genetic variations. Polygenic overlap analysis was used to test genetic correlation and to analyze s...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Fuquan Zhang, Hongbao Cao, Ancha Baranova
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2021-11-01
Schriftenreihe:Frontiers in Cardiovascular Medicine
Schlagworte:
Online Zugang:https://www.frontiersin.org/articles/10.3389/fcvm.2021.735136/full