A phylogenetic approach to study the evolution of somatic mutational processes in cancer
A method, PhyloSignare, is presented to infer mutational signatures along a tumour evolutionary tree and is used to analyse somatic genomic variations in 61 lung cancer patients, providing insights into tumour evolution.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03560-0 |