DNA repair and damage pathways in mesothelioma development and therapy

DNA repair and damage pathways in mesothelioma development and therapy

Abstract Malignant mesothelioma (MMe) is an aggressive neoplasm that occurs through the transformation of mesothelial cells. Asbestos exposure is the main risk factor for MMe carcinogenesis. Other important etiologies for MMe development include DNA damage, over-activation of survival signaling path...

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Bibliographic Details
Main Authors: Faezeh Malakoti, Niloufar Targhazeh, Erfan Abadifard, Reza Zarezadeh, Sahar Samemaleki, Zatollah Asemi, Simin Younesi, Reza Mohammadnejad, Seyed Hadi Hossini, Ansar Karimian, Forough Alemi, Bahman Yousefi
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cancer Cell International
Subjects:
Malignant mesothelioma
Malignant peritoneal mesothelioma
DNA damage repair
Signaling pathways
BRCA1 associated protein 1
BAP1
Online Access:https://doi.org/10.1186/s12935-022-02597-9

Internet

https://doi.org/10.1186/s12935-022-02597-9

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