New insights into the role of cytochrome P450 reductase (POR) in microsomal redox biology

Cytochrome P450 reductase (POR) is an essential electron transfer protein located on the endoplasmic reticulum of most cell types, and has long been appreciated for its role in cytochrome P450-mediated drug metabolism. Additional roles and electron acceptors for POR have been described, but it is la...

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Bibliographic Details
Main Author: Todd D. Porter
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512000184