Facilitating plasmid nuclear delivery by interfering with the selective nuclear pore barrier

Abstract Nuclear pore complexes (NPCs) are sophisticated transporters assembled from diverse proteins termed nucleoporins (Nups). They control all nucleocytoplasmic transport and form a stringent barrier between the cytosol and the nucleus. While selective receptor‐mediated transport enables translo...

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Bibliographic Details
Main Authors: Ihab Azzam, Ivan Liashkovich, Isabelle Luchtefeld, Ivan U. Kouzel, Victor Shahin
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10136