The Epipeptide YydF Intrinsically Triggers the Cell Envelope Stress Response of Bacillus subtilis and Causes Severe Membrane Perturbations

The Epipeptide YydF Intrinsically Triggers the Cell Envelope Stress Response of Bacillus subtilis and Causes Severe Membrane Perturbations

The Gram-positive model organism and soil bacterium Bacillus subtilis naturally produces a variety of antimicrobial peptides (AMPs), including the ribosomally synthesized and post-translationally modified AMP YydF, which is encoded in the yydFGHIJ locus. The yydF gene encodes the pre-pro-peptide, wh...

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Bibliographic Details
Main Authors: Philipp F. Popp, Alhosna Benjdia, Henrik Strahl, Olivier Berteau, Thorsten Mascher
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
Bacillus subtilis
antimicrobial peptides
cell envelope stress response
RiPP
epipeptide
membrane depolarization
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00151/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00151/full

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