Understanding fluconazole tolerance in Candida albicans: implications for effective treatment of candidiasis and combating invasive fungal infections

Understanding fluconazole tolerance in Candida albicans: implications for effective treatment of candidiasis and combating invasive fungal infections

ABSTRACT: Objectives: Fluconazole (FLC) tolerant phenotypes in Candida species contribute to persistent candidemia and the emergence of FLC resistance. Therefore, making FLC fungicidal and eliminating FLC tolerance are important for treating invasive fungal diseases (IFDs) caused by Candida species...

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Bibliographic Details
Main Authors: Yanru Feng, Hui Lu, Malcolm Whiteway, Yuanying Jiang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Fluconazole tolerance
Fluconazole synergistic lethal targets
Fluconazole synergistic lethal adjuvants
Invasive fungal disease
Candida albicans
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716523001881

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http://www.sciencedirect.com/science/article/pii/S2213716523001881

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