Mendelian randomization analysis to assess a causal effect of haptoglobin on macroangiopathy in Chinese type 2 diabetes patients

Mendelian randomization analysis to assess a causal effect of haptoglobin on macroangiopathy in Chinese type 2 diabetes patients

Abstract Background Haptoglobin (Hp) functions as an antioxidant by binding with haemoglobin. We investigated whether serum Hp has a causal effect on macroangiopathy via Mendelian randomization (MR) analysis with common variants of the Hp gene in Chinese patients with type 2 diabetes. Methods A tota...

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Bibliographic Details
Main Authors: Shiyun Wang, Jie Wang, Rong Zhang, Tao Wang, Dandan Yan, Zhen He, Feng Jiang, Cheng Hu, Weiping Jia
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cardiovascular Diabetology
Subjects:
Haptoglobin
Mendelian randomization
Macroangiopathy
Type 2 diabetes
Online Access:http://link.springer.com/article/10.1186/s12933-018-0662-7

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http://link.springer.com/article/10.1186/s12933-018-0662-7

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