Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly

Pancreatic cancer is a devastating disease with a dismal prognosis and poor treatment outcomes. Searching for new agents for pancreatic cancer treatment is of great significance. We previously identified a novel activity of compound C150 to inhibit pancreatic cancer epithelial-to-mesenchymal transit...

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Bibliographic Details
Main Authors: Tao Wang, Ping Chen, Scott Weir, Michael Baltezor, Frank J. Schoenen, Qi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.870473/full