Vaccination against connective tissue growth factor attenuates the development of renal fibrosis

Vaccination against connective tissue growth factor attenuates the development of renal fibrosis

Abstract There is a critical need for efficient treatment of chronic kidney disease (CKD). Renal fibrosis is a final common pathway to end-stage renal disease independent of the underlying etiology, and connective tissue growth factor (CTGF) is a well-recognized profibrotic factor in fibrosis of var...

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Bibliographic Details
Main Authors: Takashin Nakayama, Tatsuhiko Azegami, Kaori Hayashi, Akihito Hishikawa, Norifumi Yoshimoto, Ran Nakamichi, Erina Sugita, Hiroshi Itoh
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15118-5

Internet

https://doi.org/10.1038/s41598-022-15118-5

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