Development of RT h-CLAT, a Rapid Assessment Method for Skin Sensitizers Using THP-1 Cells as a Biosensor

In recent years, in vitro skin sensitization assays have been recommended as animal-free alternatives for the safety assessment of cosmetics and topical drugs, and these methods have been adopted in OECD test guidelines. However, existing assays remain complex and costly. To address this, we recentl...

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Bibliographic Details
Main Authors: Hiroki Koyama, Ayami Maeda, Peiqi Zhai, Keiichiro Koiwai, Kouichi Kurose
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/14/12/632