Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B.

Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B.

Mucopolysaccharidosis (MPS) IIIB (Sanfilippo Syndrome type B) is caused by a deficiency in the lysosomal enzyme N-acetyl-glucosaminidase (Naglu). Children with MPS IIIB develop disturbances of sleep, activity levels, coordination, vision, hearing, and mental functioning culminating in early death. T...

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Bibliographic Details
Main Authors: Coy D Heldermon, Anne K Hennig, Kevin K Ohlemiller, Judith M Ogilvie, Erik D Herzog, Annalisa Breidenbach, Carole Vogler, David F Wozniak, Mark S Sands
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1945015?pdf=render

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http://europepmc.org/articles/PMC1945015?pdf=render

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