Direct additive-free N-formylation and N-acylation of anilines and synthesis of urea derivatives using green, efficient, and reusable deep eutectic solvent ([ChCl][ZnCl2]2)

Direct additive-free N-formylation and N-acylation of anilines and synthesis of urea derivatives using green, efficient, and reusable deep eutectic solvent ([ChCl][ZnCl2]2)

Abstract In the current report, we introduce a simple, mild efficient and green protocol for N-formylation and N-acetylation of anilines using formamide, formic acid, and acetic acid as inexpensive, nontoxic, and easily available starting materials just with heating along stirring in [ChCl][ZnCl2]2...

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Bibliographic Details
Main Authors: Fatemeh Abbasi, Ali Reza Sardarian
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
N-Formylation
N-Acylation
Deep eutectic solvent
Unsymmetrical ureas
Acetic acid
Formamide
Online Access:https://doi.org/10.1038/s41598-024-57608-8

Internet

https://doi.org/10.1038/s41598-024-57608-8

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