Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

Conformationally restrained polyamine analog PG11047 is a well-known drug candidate that modulates polyamine metabolism and inhibits cancer cell growth in a broad spectrum of cancers. Here, we report a structure–activity relationship study of the PG11047 analogs (HPGs) containing alkyl chains of var...

ver descrição completa

Detalhes bibliográficos
Principais autores: Diptesh Sil, Sudipta Panja, Chinmay M. Jogdeo, Raj Kumar, Ao Yu, Cassandra E. Holbert, Ling Ding, Jackson R. Foley, Tracy Murray Stewart, Robert A. Casero, David Oupický
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-04-01
coleção:Molecules
Assuntos:
polyamine analogs
PG11047
self-assembly
spermine oxidase
cancer therapy
Acesso em linha:https://www.mdpi.com/1420-3049/27/8/2441

Internet

https://www.mdpi.com/1420-3049/27/8/2441

Registros relacionados