Human stem cell modeling of neuropsychiatric disorders: from polygenicity to convergence

Neuropsychiatric disorders (NPD) are prevalent and devastating, posing an enormous socioeconomic burden to modern society. Recent genetic studies of NPD have identified a plethora of common genetic risk variants with small effect sizes and rare risk variants of high penetrance. While exciting, there...

Full description

Bibliographic Details
Main Author: Duan Jubao
Format: Article
Language:English
Published: De Gruyter 2023-08-01
Series:Medical Review
Subjects:
Online Access:https://doi.org/10.1515/mr-2023-0016