Human stem cell modeling of neuropsychiatric disorders: from polygenicity to convergence
Neuropsychiatric disorders (NPD) are prevalent and devastating, posing an enormous socioeconomic burden to modern society. Recent genetic studies of NPD have identified a plethora of common genetic risk variants with small effect sizes and rare risk variants of high penetrance. While exciting, there...
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Format: | Article |
Language: | English |
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De Gruyter
2023-08-01
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Series: | Medical Review |
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Online Access: | https://doi.org/10.1515/mr-2023-0016 |