Liquiritigenin promotes osteogenic differentiation and prevents bone loss via inducing auto-lysosomal degradation and inhibiting apoptosis

Liquiritigenin promotes osteogenic differentiation and prevents bone loss via inducing auto-lysosomal degradation and inhibiting apoptosis

Osteoporosis (OP) is a debilitating skeletal abnormality involving bone remodeling and bone cell homeostasis characterized by decreased bone strength and high fracture risk. A novel therapeutic intervention for OP by manipulating cellular autophagy–apoptosis processes to promote skeletal homeostasis...

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Bibliographic Details
Main Authors: Yu Qiu, Yueyang Zhao, Zhimin Long, Aijia Song, Peng Huang, Kejian Wang, Ling Xu, David Paul Molloy, Guiqiong He
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
Series:Genes and Diseases
Subjects:
Apoptosis
Auto-lysosomal degradation
Liquiritigenin
Osteogenic differentiation
Osteoporosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304221000891

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http://www.sciencedirect.com/science/article/pii/S2352304221000891

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