Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

Abstract Background Parkinson’s disease (PD) affects an estimated 7 to 10 million people worldwide, and only symptomatic treatments are presently available to relieve the consequences of brain dopaminergic neurons loss. Neuronal degeneration in PD is the consequence of neuroinflammation in turn infl...

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Bibliographic Details
Main Authors: Natasa Kustrimovic, Cristoforo Comi, Luca Magistrelli, Emanuela Rasini, Massimiliano Legnaro, Raffaella Bombelli, Iva Aleksic, Fabio Blandini, Brigida Minafra, Giulio Riboldazzi, Andrea Sturchio, Marco Mauri, Giorgio Bono, Franca Marino, Marco Cosentino
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Parkinson’s disease
CD4+ T lymphocytes
Th1
Th2
Th17
Treg
Online Access:http://link.springer.com/article/10.1186/s12974-018-1248-8

Internet

http://link.springer.com/article/10.1186/s12974-018-1248-8

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