Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation

Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation

Our previous study demonstrated that ovarian wild-type P53-induced phosphatase 1 (WIP1) expression decreased with age. We hypothesized that WIP1 activity was related to ovarian aging. The role of WIP1 in regulating ovarian aging and its mechanisms remain to be elucidated. Adult female mice with or w...

Full description

Bibliographic Details
Main Authors: Su Zhou, Yueyue Xi, Yingying Chen, Fangfang Fu, Wei Yan, Milu Li, Yaling Wu, Aiyue Luo, Ya Li, Shixuan Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
ovarian aging
WIP1
follicular atresia
apoptosis
primordial follicle activation
Online Access:https://www.mdpi.com/2073-4409/11/23/3920

Internet

https://www.mdpi.com/2073-4409/11/23/3920

Similar Items