Consistent Long-Term Therapeutic Efficacy of Human Umbilical Cord Matrix-Derived Mesenchymal Stromal Cells After Myocardial Infarction Despite Individual Differences and Transient Engraftment

Human mesenchymal stem cells gather special interest as a universal and feasible add-on therapy for myocardial infarction (MI). In particular, human umbilical cord matrix-derived mesenchymal stromal cells (UCM-MSC) are advantageous since can be easily obtained and display high expansion potential. U...

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Main Authors: Tiago L. Laundos, Francisco Vasques-Nóvoa, Rita N. Gomes, Vasco Sampaio-Pinto, Pedro Cruz, Hélder Cruz, Jorge M. Santos, Rita N. Barcia, Perpétua Pinto-do-Ó, Diana S. Nascimento
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.624601/full