The role of mitophagy during oocyte aging in human, mouse, and Drosophila: implications for oocyte quality and mitochondrial disease

There is a worldwide trend for women to have their first pregnancy later in life. However, as oocyte quality declines with maternal aging, this trend leads to an increase in subfertility. The cellular mechanisms underlying this decline in oocyte competence are poorly understood. Oocyte mitochondria...

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Bibliographic Details
Main Authors: Rachel T Cox, Joanna Poulton, Suzannah A Williams
Format: Article
Language:English
Published: Bioscientifica 2021-11-01
Series:Reproduction and Fertility
Subjects:
Online Access:https://raf.bioscientifica.com/view/journals/raf/2/4/RAF-21-0060.xml