WPK5, a Novel Kunitz-Type Peptide from the Leech <i>Whitmania pigra</i> Inhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency
Kunitz-type proteins or peptides have been found in many blood-sucking animals, but the identity of them in leeches remained elusive. In the present study, five Kunitz-type peptides named WPK1-WPK5 were identified from the leech <i>Whitmania pigra</i>. Recombinant WPK1-WPK5 were expresse...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/9/12/1745 |